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Statistical Methods for Contemporary Clinical Trials
Current approaches to handling rescue medication in asthma and eczema randomized controlled trials are inadequate: a systematic review
Chis Ster A, Cornelius V, Cro S
This review examines how rescue medication is defined, reported, and accounted for in randomized controlled trials in eczema and asthma populations. We found that while rescue medication is frequently permitted in trials alongside the treatment under evaluation, there is minimal attention or interest in isolating the underlying treatment effect of interest.
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