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Estimands in published protocols of randomised trials: urgent improvement needed

Kahan BC, Morris TP, White IT, Carpenter J, Cro S

This paper described a review of trial protocols published in October 2020 in Trials and BMJ Open. For each protocol is was investigated whether the estimand for the primary outcome was explicitly stated, not stated but inferable (i.e. could be constructed from the information given), or not inferable.

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