Individual participant data meta-analysis versus aggregate data meta-analysis: A case study in eczema and food allergy prevention

Eleanor Van Vogt ,Suzie Cro, Victoria R. Cornelius, Hywel C. Williams, Lisa M. Askie, Rachel Phillips, Maeve M. Kelleher, Robert J. Boyle

This paper compares Aggregate data and IPD meta-analysis. It demonstrates that using IPD enables safety, subgroup and adherence analyses not possible using only aggregate data and certainty of evidence is increased.